This course aims to explore the latest advancements in radical chemistry, focusing on the synthesis of Carbon-Carbon and Carbon-Heteroatom bonds. Participants will receive a comprehensive overview of radical chemistry, covering traditional generation strategies, radical nature, stability, and properties. Additionally, the course delves into contemporary methods for generating radical intermediates, emphasizing catalytic approaches such as photo- and electrocatalysis, including enantioselective variants. Furthermore, participants will explore the application of cutting-edge technologies like flow chemistry and mechanochemistry in radical transformations, enhancing their understanding of modern synthetic methodologies.
Please find below a bullet point description of the program:
Introduction
o Radical properties: reactivity profiles, philicity, persistency/stability, analysis (EPR)
o Classical generation approaches: HAT, XAT, SET
o Merger with catalytic manifolds
Modern Strategies
o Photocatalysis
o Electrochemistry
o Photo-Electrochemistry
Technologies applied to photocatalysis and electrochemistry
o Flow
o Mechanochemistry
Course duration: 24 hours
- Teacher: Giulio Goti
- Teacher: Daniele Mazzarella